We must not forget that we are getting used to things, even to disadvantages or design-curiosities - both, Leica and Nikon-users.
When I finally decided to invest into photography again 13 years ago and buy a "proper" camera (instead of my Pentax) I considered Canon, Nikon (F5), Contax AX and Leica R8.
It was the first time I handled another SLR for decades, I wasn't used to any of the systems and I was shocked by the buttons, complexity of the japanese brands while the R8 felt organic, designed from the ground up (instead of adding additional buttons with every generation). Maybe it's just me (I'm German, so I share the design-mentality of a German-design-approach) but just look at the switch for the exposure method. In the R8 it was perfectly integrated underneath the time wheel - where is it on the F5 (or D3x)? At the side of the prism, who came up with this idea? Just because there was space left?
I would love to hear how a Japanese feels about that, maybe it's the opposite?
The S2 is menu-based, the buttons are "case-sensitive" or programmable. YOU choose which buttons you always need and program them - the primary controls are clean and intuitive - the camera feels "organic".
One question, because I didn't had the time on Photokina:
How do you move a zoomed image on the display when you don't have buttons for up/down/left/right? Diagonally with the four buttons surrounding the display?