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YES... this was my roundabout way of saying that we humans embrace all sorts of technology and very rarely does it disappear. I suspect someone is doing cave painting somewhere even now. When photography came along did we drop painting/pencils/chalk etc - no. Same when digital came along some stuck to film. Sure.. the quantities of users of any medium vary.
Are these chemicals toxic? Likely!Photographers had careers coating their own plates in the field because they had to be shoot wet. I can't see why anyone dedicated enough can't do the same (in fact a few do today). When Kodak started coating their own film, they did not need 20th technology. I am sure someone could come up with a air knife in their basement.