If I'm photographing a person, the first image, and the first image in any subsequent light change, is with a CCP held next to the subject's face. As my antique Novatron strobe systems are neither consistent or comparable, this is pretty much a must.
If the subject is not a person I just stick it in the center of the scene wherever is convient and don't generate a new profile. As I don't do people very often that's the most common situation.
I generally use it just for purposes of obtaining a white balance, but I will occasionally generate a profile just to see what there is to see. Mostly I just use the white balance and would be just as well served with using a straight white balance checker. Probably do just as well with a coffee filter
Having decided that, for me at least,
pleasing color is more important than
accurate color, this seems to work out ok. YMMV. If you're not using a calibrated and profiled monitor and printer, this may or may not be terribly productive anyway.
I do notice that there is a difference between using the CCP and an ExpoDisk. Or pretty much any other white balance target for that matter. It also makes a difference depending on how the device is angled and how it picks up reflected light from surrounding objects.
According to Andrew Rodney (the Digital Dog website), you are only profiling the illuminant and making multiple profiles is not productive and only needs to be done once. I'm not real convinced of that myself, but then I only do this for fun.
. Since it's there and it's no big issue generating a new profile just to try out I sorta think "Why not".
I'm probably messing things up further since in the Texas border version of English we say
Color instead of
Colour